Aurel Popescu, Anca Nicoleta Şuţan, Elena Popa,Andreea Cristina Vasile
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Allium cepa test, pesticides, cytogenetic effects, mitotic index, chromosomal abnormalities, mutagenicity,
genotoxic potential.
This paper presents a synthesis of mutagenic potential of a few pesticides. Cytotoxicity tests, using plant test systems in vivo, such as Allium cepa, are validated by the similar results performed in animal testing in vitro. Cytogenetic tests are usefulness for identifying and evaluating the damaging effects of pesticides present in various concentrations under different exposure times on living organisms. Mutagenic potential of different pesticides used can be detected cytologically by cellular inhibition (mitotic index and replication index are used as indicators of adequate cell proliferation), disruption in metaphase, induction of chromosomal aberrations, numerical and structural, ranging from chromosomal fragmentation to the disorganization of the mitotic spindle, and consequently of all subsequent dependent mitotic phases.
